The first medal at London 2012 will awarded in shooting with Republic of Korea, Sweden and Great Britain expected to feature strongly throughout the eight days of competition.
Equestrian
Great Britain has been dominant recently inside the equestrian arena, though Germany, Denmark and the Netherlands will be pushing for the podium in London.
The IPC has chosen 50 top athletes to provide video blogs to the world during London 2012.
Five individuals, including Paralympians and coaches, will be inducted into the Visa Paralympic Hall of Fame on Thursday (30 August).
Table Tennis
Despite starting competition early on the day after the Opening Ceremony, table tennis player Mateja Pintar is eager to carry Slovenia’s flag.
Great Britain
IPC President Sir Philip Craven says: "All the ingredients are there for best Paralympic Games ever."
Musicians across UK will perform their own unique renditions of Viva la Vida at the same time before the Paralympic Games Closing Ceremony.
Take a trip back into time as we approach the Paralympics, refreshing your memory on who are some of the best to have ever competed at the Paralympic Games.
Cyclist Simon Richardson will light the Paralympic ceremonial cauldron outside City Hall in Cardiff on Monday.
Athletics
Here are five storylines many Paralympic fans may not be aware of but could steal the headlines once the London 2012 competition begins.